
According to SCORENigeria, captain Wilfred Ndidi, Samuel Chukwueze and Al-Ittihad striker George Ilenikhena are set to start on the bench.
Raphael Onyedika, Frank Onyeka and Taiwo Awoniyi will all come into the starting line-up in their places.
Chelle is, however, expected to retain the same back four that started Friday’s 2-1 victory over Madagascar’s Barea.
Atlético Madrid winger Ademola Lookman and striker Akor Adams are also expected to start against the Wild Dogs.
Guinea-Bissau will host the Super Eagles at the September 24 Stadium in Bissau, with kick-off scheduled for 5pm Nigerian time.
AFCON 2027Q: Chelle shakes up Super Eagles XI for Guinea-Bissau clash
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